Lodewijk XVI-trapeinde, met medaillon van Broeder Cöme - Inventaire archéologique - fiche n° 347

Analyse van discrete-tijd-wachtlijnsystemen met meerdimensionale toestandsruimte

Bez nazwy-347

Purine N-oxides. XVI. Oncogenic derivatives of xanthine and guanine.

The oxidation of guanine to an N-oxide and its hydrolysis to a xanthine N-oxide are rejorted. The s.c. administration of the xanthine N-oxide to rats for 6 months resulted in development of a variety of tumors. There were 1 liposarcoma, 3 fibrosarcomas, 1 nmmmary adenocarcinoma, 3 fibrohlastic tumors, 2 rhabdomyosarcomas, and 1 epideiinoid carcinoma at the site of injection and elsewhere in 11 ...

Npgrj_nmeth_1188 347..353

We developed an algorithm, Lever, that systematically maps metazoan DNA regulatory motifs or motif combinations to sets of genes. Lever assesses whether the motifs are enriched in cis-regulatory modules (CRMs), predicted by our PhylCRM algorithm, in the noncoding sequences surrounding the genes. Lever analysis allows unbiased inference of functional annotations to regulatory motifs and candidat...

Nen20845 330..347

It is well established that hypoxia causes excess accumulation of glutamate in developing neural tissues. This study aimed to elucidate the mechanism by which glutamate can cause retinal ganglion cell (RGC) death through the N-methyl-D-aspartate (NMDA) receptors (NR) in the developing retina. One-day-old Wistar rats were exposed to hypoxia for 2 hours and then killed at different time points. N...